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The 16-10A1 antibody blocks binding of CTLA-4 Ig to CD80 as well as T-cell activation by Con A-elicited peritoneal exudate cells or CD80-transfected cell lines. However, the 16-10A1 antibody alone is not able to block T-cell activation by antigen-presenting cells. The 16-10A1 antibody may reportedly block the binding of another CD80-specific ...
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Get PriceDescription. The 16-10A1 monoclonal antibody specifically recognizes CD80 (B7-1). This member of the Ig superfamily, like CD86 (B7-2), can bind to either CD28 or CD152 (CTLA-4) and provide either costimulatory or coinhibitory signals to T cells, respectively.
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Get Price2020-9-8 · production of recombinant proteins and monoclonal antibodies in Chinese Hamster Ovary (CHO) cells. This medium is designed to be used in conjunction with any feed medium; however, it achieves maximum performance with BalanCD CHO Feed 4. Product Description BalanCD CHO Growth A is provided without L-Glutamine to extend shelf life.
Get Price2013-12-24 · were routinely maintained in CD-CHO medium supple- mented with 8 mM glutamine and 10 mL/L hypoxan- thine/thymidine supplement (all from Invitrogen, UK), shaken at 140 rpm in a humidified 37˚C incubator in 8% CO. 2. Cell concentration and viability were measured using the trypan blue dye exclusion method. 2.2. DNA Plasmid
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